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Clopidogrel and CBD Interaction by Matthew Roman, MDNature CYP2C19, however, is the enzyme responsible for the breakdown of N-desmethylclobazam and the theoretical clopidogrel and CBD interaction discussed below. Clopidogrel and CYP2C19 Activity Clopidogrel (Plavix®) is a frequently prescribed drug indicated for patients with myocardial infarction (MI; aka heart attack) or those with stents placed to prevent such a catastrophe. Plavix Uses, Dosage & Side Effects -

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